Bacterial vaginosis

Cause of Bacterial vaginosis

Bacterial vaginosis has a polymicrobial aetiology. Organisms involved in the aetiology of bacterial vaginosis include anaerobes Mobiluncus sp. and Prevotella sp., Gardnerella vaginalis, and Mycoplasma hominis

Bacterial vaginosis: How to find out if you have it

BV is the most common vaginal infection in women of childbearing age. With BV, the normal balance of bacteria in the vagina is changed so that there are more “harmful” bacteria and fewer “good” bacteria. Antibiotics are used to treat and cure BV.

Bacterial vaginosis: How you get it

Not much is known about how women get BV. Any woman can get BV. But BV rarely occurs in women who have never had vaginal sex. Having BV can increase a woman’s risk of getting an STI, including HIV. These things put you more at risk for BV:
  • Having a new or many sex partners
  • Douching
  • Using an intrauterine device (IUD) for birth control
  • Not using a condom
  • You CANNOT get BV from such objects as toilet seats, bedding, or swimming pools.

Symptoms of Bacterial vaginosis

Most women have no symptoms. Women with symptoms may have:
  • Vaginal itching
  • Pain when urinating
  • Discharge with a fishy odor

Your doctor will test a sample of fluid from your vagina. Your doctor also may be able to see signs of BV, like a grayish-white discharge, during an exam.

Recommended treatments of Bacterial vaginosis

Treatment regimes have similar cure rates of 70-80% after four weeks. Compliance with therapy may results in a symptomatic cure but a microbiological cure, so relapse after single dose metronidazole (2g) treatment is common; 60% of women relapse in three months.
Clindamycin is effective but also kills lactobacilli, and topical treatment may predispose patient to vulvovaginal candidiasis. Intravaginal clindamycin can cause condom failure.
Metronidazole 2g single doze (C (2), E (2), U, W (2)).
Metronidazole 400mg twice daily for five to seven days (C, E, U, W).
Metronidazole 0.75% gel daily for five days (C, E, U, W, (2)).
Clindamycin 2% cream 5g daily for seven days (C, E, U, and W (2)).
Clindamycin ovules 100mg daily for three days (C).
Clindamycin 300mg orally twice daily for seven days (C, E, W (2).)
Prophylaxis for surgical interventions: rectal metronidazole 1g or intravenous metronidazole 500mg.


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